What is anti SSA and SSB?

What is anti SSA and SSB?

Anti‐SSA and ‐SSB antibodies are clinically important antinuclear antibody (ANA) in patients with systemic rheumatic diseases. These antibodies are found in Sjögren’s syndrome (SS), as well as other systemic autoimmune diseases (ADs), such as systemic lupus erythematosus (SLE), myositis, scleroderma, etc.

What is anti-La SSB test?

Anti-Ro/SSA and Anti-La/SSB are antibodies found mostly in people with systemic lupus (30-40%) and primary Sjogren’s syndrome. They are also commonly found in people with lupus who have tested negative for anti-nuclear antibodies.

What is Anti-Ro positive?

Anti-Ro antibodies can be found in patients with a variety of autoimmune conditions including Lupus, Sjögren’s syndrome and rheumatoid arthritis. It can also be found in a small number of asymptomatic women who don’t have an associated medical disorder.

What causes Ro antibody?

SS-A/Ro antibodies occur in patients with several different connective tissue diseases including Sjogren syndrome, an autoimmune disease that involves primarily the salivary and lachrymal glands (up to 90% of cases); lupus erythematosus (LE) (40%-60% of cases); and rheumatoid arthritis.

What is SSA Ro antibody?

SSa (Ro) antibodies are found in Sjogren’s, lupus, and related disorders. In pregnancy, SSa antibodies increase the risk of neonatal lupus and heart block. SSa antibodies are autoantibodies, which means that they target the body’s own proteins rather than infectious or other foreign protein antigens.

What are SSA antibodies?

SSa antibodies are autoantibodies, which means that they target the body’s own proteins rather than infectious or other foreign protein antigens.

What is Anti – SSA blood test?

The SSA Antigen. The SSA antigen is also referred to as the “Ro/SSA” antigen.

  • The Test. The test that is given to identify SSA and SSB antigens in the blood stream often includes a CBC (complete blood count) as well as a liver and
  • Symptoms of Positive SSA.
  • SSA Markers and Other Diseases.
  • SSA and Systemic Lupus.
  • What is a positive anti – SSA antibody?

    A positive result for SS-A/Ro antibodies is consistent with connective tissue disease, including Sjogren syndrome, lupus erythematosus (LE), or rheumatoid arthritis. A positive result for SS-A/Ro antibodies in a woman with LE prior to delivery indicates an increased risk of congenital heart block in the neonate.